Andarine (S-4)

What it is, how it works and what are the benefits.

What is Andarine (S-4)?

Andarine, also known as S4 is a selective androgen receptor modulator that is currently still under investigation. Andarine was developed by GTx to treat various conditions such as osteoporosis, muscle wasting diseases and prostatic hyperthropy. S4 will help you preserve lean muscle while also helping your body stimulate fat loss. S4 will help give you that dry shredded look, binding to the androgen receptors very rapid. Because this sarm is very mild, recovering from the cycle is easy.

‘Andarine dried me out like no other supplement did, it gave me a nice hard look whilst adding lean muscle’

How does Andarine works?

S4 is a selective androgen receptor modulator, it will bind directly to the androgen receptors in your muscles and bones. This will cause anabolic activity and increased protein synthesis, making it easier to gain muscle. The SARMs work in the same way as steroids do, but SARMs do not heavily suppress the male hormone system and they do not convert to estrogen. Because S-4 has such mild side effects it has been very populair amongst athletes, bodybuilders and fitness enthousiasts and is often stacked with other SARMs.

Andarine molecule structure

Andarine protocols

Although you can run S-4 perfectly by itself, it is suggested to stack Andarine with other SARMs. For example MK677, Ostarine and S4. If you decide to run Andarine by itself the suggested starting dose is atleast 50mg and you can always up the dose if you feel comfortable doing so. If the side effects are becoming too much, do NOT up your doseage. The cycle should be atleast 8 weeks minimum and up to 12 weeks to get the most out of it.
When stacking S-4 with other SARMs, a minimum dose of 25-50mg should be taken. S-4 has a half life of about 4 to 6 hours, so you should split your dose in two. Often S4 is compared to winstrol, because it increases definition and hardness when you are low bodyfat. We suggest starting a S4 cycle with a lean physique, when you start lean you can really see why they compare s4 to winstrol. Andarine should be taken 5 days on, 2 days off if you suffer from the vision side effects.

Andarine experiences

Andarine is a great SARM if you know what you are doing. People report rapid strength and muscle gains, along with increased vascularity while being in a caloric deficit! Although the vision side effects can be annoying, not a lot of users have reported it being a real problem during their cycle. For most people the sweet spot seems to be at around 50 to 100mgs a day for 8 to 12 weeks.

What are the benefits and side effects of Andarine?

S4 is one of the most investigated SARM out there. Various studies have shown that S4 definitely has earned its place in the SARMs group.

Benefits of S4:

  • Improvement of lean muscle;
  • Improvement of stamina and endurance;
  • Increased bone density;
  • Enhance Quality of life (QOL).

Side effects of S4:

  • Temporary vision concerns;
  • Mild suppression of testosterone levels.

Andarine improves endurance

Literature